Microbial Bioengineering Laboratory
Laboratory HeadMgr. Pavel Dvořák, Ph.D.
(ORCID ID: 0000-0002-3215-4763)
Employees and students in this laboratory specialize in engineering bacterial and microbial metabolic pathways for biotechnology. The aim of the research group is to link microbiology with other disciplines, especially molecular biology, biochemistry and bioinformatics, and work on interdisciplinary projects that contribute to the basic knowledge of studied systems but also have a significant application potential. The main topics of the laboratory are biotechnological processing of plant biomass (lignocellulose) and biodegradation of waste materials (toxic environmental pollutants, plastics). The safe robust strains of bacteria Escherichia coli and Pseudomonas putida are mainly used as host organisms. For the purpose of more efficient utilization and valorization of carbohydrates from plant biomass or easier degradation of recalcitrant pollutants, bacteria are modified by modern methods of synthetic biology and metabolic engineering. Synthetic biology tools are also applied for preparation of artificial bacterial consortia which should be able to perform the desired functions with higher efficiency and in longer term than individual recombinant microorganisms. The laboratory provides a lecture and practical classes on the subject Special methods for analysis of microorganisms (Bi6721 and Bi6721c) for undegraduate students and new advanced subject Introduction to the synthetic biology and metabolic engineering of microorganisms is in preparation.
Contact: Kamenice 5/A25, 625 00 Brno, Czech Republic
tel.: +420 549 493 396